General Information
SPKB ID SPKB02618
Signal sequence MEALMARGALTGPLRALCLLGCLLSHAAA
Length 29
Organism Homo sapiens (Human)
UniProt ID P08253,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02618.cif
Physicochemical Information
Molecular weight 2924.59214
Aliphatic index 131.7241379
Isoelectric point 8.242962328
Charge (pH=7) 0.966712459
Topological polar surface area 1099.57
Aromaticity 0
Average rotatable bonds 3.275862069
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 40
X logP energy -9.02276
Hydropathy
Literature Information
Title H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.
DOI NA,
Publication Year 1988
PubMed ID 2834383,
Patent ID NA,