SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02617

Signal sequence   MARGSAVAWAALGPLLWGCALG

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P08236,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02617.cif

Structure  SPKB02617.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2171.60604

Aliphatic index  111.3636364

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  779.34

Aromaticity  0.090909091

Average rotatable bonds  2.909090909

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  27

X logP energy  -5.04283

Hydropathy 



Literature Information


Title  Characterization of the subunits and sugar moiety of human placental and leukemic beta-glucuronidase.

DOI  10.1515/bchm3.1992.373.1.57,

Publication Year  1992

PubMed ID  1311180,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.