SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02616

Signal sequence   MKRVITLFAVLLMGWSVNAWS

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P08191,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Fimbrium

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5MTS,

Predicted Structure ID  SPKB02616.cif

Structure  SPKB02616.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2422.97524

Aliphatic index  125.2380952

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  868.6

Aromaticity  0.142857143

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  30

X logP energy  -3.25213

Hydropathy 



Literature Information


Title  Purification of the Escherichia coli type 1 pilin and minor pilus proteins and partial characterization of the adhesin protein.

DOI  10.1128/jb.170.8.3350-3358.1988,

Publication Year  1988

PubMed ID  2900235,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.