SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02613

Signal sequence   MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWG

Length  34

Organism  Homo sapiens (Human)

UniProt ID  P08174,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3IYP,

Predicted Structure ID  SPKB02613.cif

Structure  SPKB02613.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3593.51994

Aliphatic index  172.0588235

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  1197.02

Aromaticity  0.029411765

Average rotatable bonds  3.147058824

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  42

X logP energy  -2.42746

Hydropathy 



Literature Information


Title  Isolation of two forms of decay-accelerating factor (DAF) from human urine.

DOI  10.1016/0304-4165(91)90171-c,

Publication Year  1991

PubMed ID  1712233,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.