SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02611

Signal sequence   MNVLLGSVVIFATFVTLCNA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P08118,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02611.cif

Structure  SPKB02611.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2112.57334

Aliphatic index  146

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  763.09

Aromaticity  0.1

Average rotatable bonds  3.3

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -5.2379

Hydropathy 



Literature Information


Title  Newly identified proteins in human nasal lavage fluid from non-smokers and smokers using two-dimensional gel electrophoresis and peptide mass fingerprinting.

DOI  NA,

Publication Year  2002

PubMed ID  11788998,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.