General Information
SPKB ID SPKB02610
Signal sequence MKSGSGGGSPTSLWGLLFLSAALSLWPTSG
Length 30
Organism Homo sapiens (Human)
UniProt ID P08069,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6JK8,
Predicted Structure ID SPKB02610.cif
Physicochemical Information
Molecular weight 2966.40134
Aliphatic index 84.66666667
Isoelectric point 9.700002532
Charge (pH=7) 0.997689266
Topological polar surface area 1129.31
Aromaticity 0.1
Average rotatable bonds 3.033333333
Number of hydrogen bond donors 41
Number of hydrogen bond acceptors 42
X logP energy -13.1448
Hydropathy 
Literature Information
Title Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.
DOI 10.1002/j.1460-2075.1986.tb04528.x,
Publication Year 1986
PubMed ID 2877871,
Patent ID NA,
