SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02608

Signal sequence   MALEKSLVRLLLLVLILLVLGWVQPSLG

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P07998,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02608.cif

Structure  SPKB02608.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3087.92774

Aliphatic index  212.1428571

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  1064.79

Aromaticity  0.035714286

Average rotatable bonds  3.678571429

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -0.56173

Hydropathy 



Literature Information


Title  Characterization of a unique nonsecretory ribonuclease from urine of pregnant women.

DOI  10.1093/oxfordjournals.jbchem.a123757,

Publication Year  1992

PubMed ID  1587793,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.