SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02601

Signal sequence   MYSFNTLRFYLWETIVFFSLAASKEADA

Length  28

Organism  Rattus norvegicus (Rat)

UniProt ID  P07727,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02601.cif

Structure  SPKB02601.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3321.79464

Aliphatic index  80.35714286

Isoelectric point  4.42640492

Charge (pH=7)   -1.000018145

Topological polar surface area  1249.33

Aromaticity  0.25

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  43

X logP energy  -7.03713

Hydropathy 



Literature Information


Title  The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors.

DOI  10.1038/328215a0,

Publication Year  1987

PubMed ID  3037383,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.