SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02598

Signal sequence   MGPRMALPRVLLLLFLHLLLLGCRS

Length  25

Organism  Sus scrofa (Pig)

UniProt ID  P07634,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02598.cif

Structure  SPKB02598.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2833.64024

Aliphatic index  171.6

Isoelectric point  12.19926532

Charge (pH=7)   3.02690874

Topological polar surface area  978.75

Aromaticity  0.04

Average rotatable bonds  3.68

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  34

X logP energy  -2.12779

Hydropathy 



Literature Information


Title  Isolation and identification of a high molecular weight brain natriuretic peptide in porcine cardiac atrium.

DOI  10.1016/s0006-291x(88)80061-5,

Publication Year  1988

PubMed ID  3196347,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.