SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02597

Signal sequence   MYALFLLASLLGAALA

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P07602,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02597.cif

Structure  SPKB02597.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1638.04094

Aliphatic index  177.5

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  540.28

Aromaticity  0.125

Average rotatable bonds  3.1875

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  -0.3858

Hydropathy 



Literature Information


Title  Isolation and characterization of prosaposin from human milk.

DOI  10.1016/s0006-291x(05)81415-9,

Publication Year  1991

PubMed ID  1958198,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.