SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02595

Signal sequence   MNLLLILTFVAAAVA

Length  15

Organism  Homo sapiens (Human)

UniProt ID  P07478,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02595.cif

Structure  SPKB02595.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1559.97074

Aliphatic index  195.3333333

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  534.04

Aromaticity  0.066666667

Average rotatable bonds  3.266666667

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  19

X logP energy  -0.9404

Hydropathy 



Literature Information


Title  Immunoreactive anionic and cationic trypsin in human serum.

DOI  10.1016/0009-8981(89)90254-4,

Publication Year  1989

PubMed ID  2598466,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.