SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02594

Signal sequence   MNPLLILTFVAAALA

Length  15

Organism  Homo sapiens (Human)

UniProt ID  P07477,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02594.cif

Structure  SPKB02594.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1557.95484

Aliphatic index  176

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  525.25

Aromaticity  0.066666667

Average rotatable bonds  3.133333333

Number of hydrogen bond donors  17

Number of hydrogen bond acceptors  19

X logP energy  -1.0902

Hydropathy 



Literature Information


Title  Immunoreactive anionic and cationic trypsin in human serum.

DOI  10.1016/0009-8981(89)90254-4,

Publication Year  1989

PubMed ID  2598466,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.