SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02593

Signal sequence   MGITAGKSVLVLLAFLAFASCCYA

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  P07456,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02593.cif

Structure  SPKB02593.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2450.01024

Aliphatic index  126.25

Isoelectric point  8.221165971

Charge (pH=7)   0.872889419

Topological polar surface area  839.56

Aromaticity  0.125

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -5.0057

Hydropathy 



Literature Information


Title  A heparin-binding erythroid cell stimulating factor from fetal bovine serum has the N-terminal sequence of insulin-like growth factor II.

DOI  10.1016/0006-291x(90)90844-d,

Publication Year  1990

PubMed ID  2302223,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.