SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02590

Signal sequence   MFSLKALLPLALLLVSANQVAA

Length  22

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P07267,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02590.cif

Structure  SPKB02590.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2283.84114

Aliphatic index  173.1818182

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  818.29

Aromaticity  0.045454545

Average rotatable bonds  3.363636364

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  29

X logP energy  -3.9302

Hydropathy 



Literature Information


Title  Vacuolar and extracellular maturation of Saccharomyces cerevisiae proteinase A.

DOI  10.1002/(SICI)1097-0061(199607)12:9%3C823::AID-YEA975%3E3.0.CO;2-J,

Publication Year  1996

PubMed ID  8840499,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.