SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02589

Signal sequence   MLRRALLCLAVAALVRA

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P07237,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02589.cif

Structure  SPKB02589.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1840.36534

Aliphatic index  178.2352941

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  714.62

Aromaticity  0

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  23

X logP energy  -3.73019

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.