SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02588

Signal sequence   MNAADRMGARVALLLLLVLGSPQSGVHG

Length  28

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P07221,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02588.cif

Structure  SPKB02588.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2847.38974

Aliphatic index  128.9285714

Isoelectric point  10.39953455

Charge (pH=7)   1.089333252

Topological polar surface area  1156.65

Aromaticity  0

Average rotatable bonds  3.357142857

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  39

X logP energy  -11.55736

Hydropathy 



Literature Information


Title  Characterization of cardiac calsequestrin.

DOI  10.1021/bi00394a038,

Publication Year  1987

PubMed ID  3427023,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.