SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02585

Signal sequence   MTPLLLLAVLCLGTALA

Length  17

Organism  Rattus norvegicus (Rat)

UniProt ID  P07154,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02585.cif

Structure  SPKB02585.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1713.21024

Aliphatic index  195.2941176

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  560.59

Aromaticity  0

Average rotatable bonds  3.117647059

Number of hydrogen bond donors  20

Number of hydrogen bond acceptors  22

X logP energy  -1.2244

Hydropathy 



Literature Information


Title  Precursor of rat epidermal cathepsin L: purification and immunohistochemical localization.

DOI  10.1016/s0923-1811(99)00063-8,

Publication Year  2000

PubMed ID  10699763,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.