SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02583

Signal sequence   MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIA

Length  32

Organism  Mus musculus (Mouse)

UniProt ID  P07141,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02583.cif

Structure  SPKB02583.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3379.07844

Aliphatic index  106.875

Isoelectric point  12.02344377

Charge (pH=7)   3.874021622

Topological polar surface area  1361.63

Aromaticity  0.03125

Average rotatable bonds  3.4375

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  48

X logP energy  -15.24822

Hydropathy 



Literature Information


Title  Amino-terminal amino acid sequence of murine colony-stimulating factor 1.

DOI  10.1073/pnas.82.13.4486,

Publication Year  1985

PubMed ID  3925458,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.