SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02582

Signal sequence   MKAILIPFLSLLIPLTPQSAFA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P07102,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02582.cif

Structure  SPKB02582.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2384.98904

Aliphatic index  155.4545455

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  777.85

Aromaticity  0.090909091

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  29

X logP energy  -1.4754

Hydropathy 



Literature Information


Title  The complete nucleotide sequence of the Escherichia coli gene appA reveals significant homology between pH 2.5 acid phosphatase and glucose-1-phosphatase.

DOI  10.1128/jb.172.9.5497-5500.1990,

Publication Year  1990

PubMed ID  2168385,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.