General Information
SPKB ID SPKB02581
Signal sequence MWLLLTMASLISVLGTTHG
Length 19
Organism Homo sapiens (Human)
UniProt ID P07098,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02581.cif
Physicochemical Information
Molecular weight 2044.49804
Aliphatic index 143.6842105
Isoelectric point 7.550323994
Charge (pH=7) 0.08889339
Topological polar surface area 732.74
Aromaticity 0.052631579
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 28
X logP energy -4.337
Hydropathy 
Literature Information
Title Human gastric lipase. The N-terminal tetrapeptide is essential for lipid binding and lipase activity.
DOI 10.1111/j.1432-1033.1989.tb14855.x,
Publication Year 1989
PubMed ID 2753032,
Patent ID NA,
