General Information
SPKB ID SPKB02579
Signal sequence MKLLQRGVALALLTTFTLASETALA
Length 25
Organism Escherichia coli (strain K12)
UniProt ID P07024,
Motif 1..25
Activity Information
Pathway Sec
Natural/Artificial Natural
Subcellular location Periplasmic space
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 1USH,
Predicted Structure ID SPKB02579.cif
Physicochemical Information
Molecular weight 2633.18514
Aliphatic index 140.8
Isoelectric point 9.695027686
Charge (pH=7) 0.999461077
Topological polar surface area 1031.18
Aromaticity 0.04
Average rotatable bonds 3.52
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 36
X logP energy -8.22303
Hydropathy
Literature Information
Title Nucleotide sequence and transcriptional analysis of the E. coli ushA gene, encoding periplasmic UDP-sugar hydrolase (5'-nucleotidase): regulation of the ushA gene, and the signal sequence of its encoded protein product.
Publication Year 1986
PubMed ID 3012467,
Patent ID NA,