SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02577

Signal sequence   MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQA

Length  33

Organism  Escherichia coli (strain K12)

UniProt ID  P06971,

Motif  1..33



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9A31,

Predicted Structure ID  SPKB02577.cif

Structure  SPKB02577.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3458.10124

Aliphatic index  88.78787879

Isoelectric point  11.76841695

Charge (pH=7)   5.087151252

Topological polar surface area  1444.06

Aromaticity  0.03030303

Average rotatable bonds  3.484848485

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  51

X logP energy  -16.84336

Hydropathy 



Literature Information


Title  Protein fusions of beta-galactosidase to the ferrichrome-iron receptor of Escherichia coli K-12.

DOI  10.1128/jb.165.1.181-192.1986,

Publication Year  1986

PubMed ID  3079747,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.