SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02575

Signal sequence   MLPASPKMEHKAVVFLLLLFLKSGLG

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P06868,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02575.cif

Structure  SPKB02575.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2840.56474

Aliphatic index  135

Isoelectric point  10.50698158

Charge (pH=7)   2.089783411

Topological polar surface area  957.74

Aromaticity  0.076923077

Average rotatable bonds  3.615384615

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  36

X logP energy  -2.3382

Hydropathy 



Literature Information


Title  Complete amino acid sequence of bovine plasminogen. Comparison with human plasminogen.

DOI  10.1111/j.1432-1033.1985.tb08921.x,

Publication Year  1985

PubMed ID  3846532,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.