SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02573

Signal sequence   MTSSRLWFSLLLAAAFAGRATA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P06865,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02573.cif

Structure  SPKB02573.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2341.75634

Aliphatic index  98.18181818

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  915.16

Aromaticity  0.136363636

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  31

X logP energy  -8.25816

Hydropathy 



Literature Information


Title  Organization of the gene encoding the human beta-hexosaminidase alpha-chain.

DOI  NA,

Publication Year  1987

PubMed ID  2952641,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.