SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02571

Signal sequence   MESKALLVLTLAVWLQSLTASRGGVAA

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P06858,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02571.cif

Structure  SPKB02571.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2786.32564

Aliphatic index  137.4074074

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  1105.17

Aromaticity  0.037037037

Average rotatable bonds  3.407407407

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -9.65183

Hydropathy 



Literature Information


Title  Rapid and simple isolation procedure for lipoprotein lipase from human milk.

DOI  10.1016/0005-2760(90)90213-h,

Publication Year  1990

PubMed ID  2340307,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.