SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02570

Signal sequence   MVSIWTIALFLLGAAKA

Length  17

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P06857,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02570.cif

Structure  SPKB02570.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1805.25174

Aliphatic index  155.2941176

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  611.19

Aromaticity  0.117647059

Average rotatable bonds  3.352941176

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  22

X logP energy  -1.0255

Hydropathy 



Literature Information


Title  Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations.

DOI  NA,

Publication Year  1998

PubMed ID  9726421,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.