General Information
SPKB ID SPKB02568
Signal sequence MAFPPRRRLRLGPRGLPLLLSGLLLPLCRA
Length 30
Organism Homo sapiens (Human)
UniProt ID P06756,
Motif 1..30
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7Y1T,
Predicted Structure ID SPKB02568.cif
Physicochemical Information
Molecular weight 3354.21724
Aliphatic index 136.6666667
Isoelectric point 12.80106679
Charge (pH=7) 5.935989716
Topological polar surface area 1254.9
Aromaticity 0.033333333
Average rotatable bonds 3.5
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 40
X logP energy -7.11898
Hydropathy
Literature Information
Title A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells.
DOI 10.1016/0092-8674(89)90172-4,
Publication Year 1989
PubMed ID 2467745,
Patent ID NA,