SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02567

Signal sequence   MFLKAVVLTLALVAVAGARA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P06727,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02567.cif

Structure  SPKB02567.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2014.54384

Aliphatic index  166

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  724.37

Aromaticity  0.05

Average rotatable bonds  3.25

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -3.06243

Hydropathy 



Literature Information


Title  Biosynthesis of human preapolipoprotein A-IV.

DOI  NA,

Publication Year  1984

PubMed ID  6706947,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.