General Information
SPKB ID SPKB02566
Signal sequence MGPLMVLFCLLFLYPGLADS
Length 20
Organism Homo sapiens (Human)
UniProt ID P06681,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02566.cif
Physicochemical Information
Molecular weight 2200.74024
Aliphatic index 136.5
Isoelectric point 3.749971056
Charge (pH=7) -1.064394347
Topological polar surface area 676.4
Aromaticity 0.15
Average rotatable bonds 3.3
Number of hydrogen bond donors 23
Number of hydrogen bond acceptors 27
X logP energy 0.1739
Hydropathy
Literature Information
Title A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2.
DOI 10.1016/s0014-5793(00)01304-1,
Publication Year 2000
PubMed ID 10734221,
Patent ID NA,