SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02563

Signal sequence   MVLQTQVFISLLLWISGAYG

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P06312,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6J6Y,

Predicted Structure ID  SPKB02563.cif

Structure  SPKB02563.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2239.70074

Aliphatic index  151

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  799.11

Aromaticity  0.15

Average rotatable bonds  3.55

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.9547

Hydropathy 



Literature Information


Title  The primary structure of a monoclonic immunoglobulin-L-chain of subgroup IV of the kappa type (Bence-Jones protein Len.)

DOI  NA,

Publication Year  1975

PubMed ID  50995,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.