SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02562

Signal sequence   MDRRRMPLWALLLLWSPCTFS

Length  21

Organism  Mus musculus (Mouse)

UniProt ID  P06281,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02562.cif

Structure  SPKB02562.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2593.16404

Aliphatic index  97.61904762

Isoelectric point  10.43741523

Charge (pH=7)   1.936446134

Topological polar surface area  943.01

Aromaticity  0.142857143

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  32

X logP energy  -3.88629

Hydropathy 



Literature Information


Title  Biosynthesis of renin in mouse kidney tumor As4.1 cells.

DOI  10.1111/j.1432-1033.1997.0181a.x,

Publication Year  1997

PubMed ID  9030738,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.