General Information
SPKB ID SPKB02560
Signal sequence MHSKVTIICIRFLFWFLLLCMLIGKSHT
Length 28
Organism Homo sapiens (Human)
UniProt ID P06276,
Motif 1..28
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4TPK,
Predicted Structure ID SPKB02560.cif
Physicochemical Information
Molecular weight 3352.22464
Aliphatic index 135.7142857
Isoelectric point 9.761397722
Charge (pH=7) 3.05525967
Topological polar surface area 1117.03
Aromaticity 0.142857143
Average rotatable bonds 3.928571429
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 42
X logP energy -1.79283
Hydropathy 
Literature Information
Title Biochemical, molecular and preclinical characterization of a double-virus-reduced human butyrylcholinesterase preparation designed for clinical use.
DOI 10.1111/j.1423-0410.2010.01415.x,
Publication Year 2011
PubMed ID 20946535,
Patent ID NA,
