SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02553

Signal sequence   MTLKALLVTALALCHG

Length  16

Organism  Mus musculus (Mouse)

UniProt ID  P05555,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02553.cif

Structure  SPKB02553.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1655.08994

Aliphatic index  158.75

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  594.98

Aromaticity  0

Average rotatable bonds  3.375

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  23

X logP energy  -3.2128

Hydropathy 



Literature Information


Title  Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon.

DOI  10.1038/314540a0,

Publication Year  1985

PubMed ID  3887182,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.