General Information
SPKB ID SPKB02552
Signal sequence MKHSLNALLIFLIITSAWG
Length 19
Organism Homo sapiens (Human)
UniProt ID P05546,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02552.cif
Physicochemical Information
Molecular weight 2128.60344
Aliphatic index 154.2105263
Isoelectric point 9.702001779
Charge (pH=7) 1.088598356
Topological polar surface area 761.39
Aromaticity 0.105263158
Average rotatable bonds 3.631578947
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 27
X logP energy -2.826
Hydropathy 
Literature Information
Title Structural evidence for leucine at the reactive site of heparin cofactor II.
DOI 10.1021/bi00345a008,
Publication Year 1985
PubMed ID 3907702,
Patent ID NA,
