SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02551

Signal sequence   MAFIAALGLLMAGICPAVLC

Length  20

Organism  Rattus norvegicus (Rat)

UniProt ID  P05545,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02551.cif

Structure  SPKB02551.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1978.55814

Aliphatic index  156.5

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  607.43

Aromaticity  0.05

Average rotatable bonds  3.05

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  25

X logP energy  -0.9809

Hydropathy 



Literature Information


Title  Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats.

DOI  NA,

Publication Year  1990

PubMed ID  2398056,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.