General Information
SPKB ID SPKB02550
Signal sequence MSPFLYLVLLVLGLHATIHC
Length 20
Organism Homo sapiens (Human)
UniProt ID P05543,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4YIA,
Predicted Structure ID SPKB02550.cif
Physicochemical Information
Molecular weight 2240.79314
Aliphatic index 170.5
Isoelectric point 7.520366034
Charge (pH=7) 0.116977351
Topological polar surface area 725.48
Aromaticity 0.1
Average rotatable bonds 3.4
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 28
X logP energy -0.4197
Hydropathy 
Literature Information
Title Partial amino acid sequence of human thyroxine-binding globulin. Further evidence for a single polypeptide chain.
DOI 10.1016/0006-291x(77)91135-4,
Publication Year 1977
PubMed ID 414747,
Patent ID NA,
