SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02548

Signal sequence   MELWGAYLLLCLFSLLTQVTT

Length  21

Organism  Homo sapiens (Human)

UniProt ID  P05452,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02548.cif

Structure  SPKB02548.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2415.93124

Aliphatic index  148.5714286

Isoelectric point  3.84996161

Charge (pH=7)   -1.063065708

Topological polar surface area  842.65

Aromaticity  0.142857143

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -2.4128

Hydropathy 



Literature Information


Title  Primary structure of tetranectin, a plasminogen kringle 4 binding plasma protein: homology with asialoglycoprotein receptors and cartilage proteoglycan core protein.

DOI  10.1021/bi00395a027,

Publication Year  1987

PubMed ID  3427041,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.