General Information
SPKB ID SPKB02546
Signal sequence MVSRMVSTMLSGLLFWLASGWTPAFA
Length 26
Organism Homo sapiens (Human)
UniProt ID P05408,
Motif 1..26
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02546.cif
Physicochemical Information
Molecular weight 2860.44284
Aliphatic index 93.84615385
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 996.89
Aromaticity 0.153846154
Average rotatable bonds 3.346153846
Number of hydrogen bond donors 37
Number of hydrogen bond acceptors 37
X logP energy -5.96983
Hydropathy 
Literature Information
Title Isolation and NH2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus.
DOI 10.1016/0003-9861(83)90063-2,
Publication Year 1983
PubMed ID 6625600,
Patent ID NA,
