SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02545

Signal sequence   MKILLLCVALLLTWDNGMVLG

Length  21

Organism  Rattus norvegicus (Rat)

UniProt ID  P05371,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02545.cif

Structure  SPKB02545.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2316.94704

Aliphatic index  180.952381

Isoelectric point  6.160569088

Charge (pH=7)   -0.063838966

Topological polar surface area  787.75

Aromaticity  0.047619048

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -0.9223

Hydropathy 



Literature Information


Title  Rat clusterin isolated from primary Sertoli cell-enriched culture medium is sulfated glycoprotein-2 (SGP-2).

DOI  NA,

Publication Year  1988

PubMed ID  3415696,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.