SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02544

Signal sequence   MLRRALLCLALTALFRAGAG

Length  20

Organism  Bos taurus (Bovine)

UniProt ID  P05307,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02544.cif

Structure  SPKB02544.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2117.64504

Aliphatic index  142

Isoelectric point  12.19926402

Charge (pH=7)   2.93599965

Topological polar surface area  822.15

Aromaticity  0.05

Average rotatable bonds  3.5

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  27

X logP energy  -5.65539

Hydropathy 



Literature Information


Title  Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex.

DOI  NA,

Publication Year  1990

PubMed ID  2351674,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.