General Information
SPKB ID SPKB02542
Signal sequence MNSFSTSAFGPVAFSLGLLLVLPAAFPAP
Length 29
Organism Homo sapiens (Human)
UniProt ID P05231,
Motif 1..29
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8QY5,
Predicted Structure ID SPKB02542.cif
Physicochemical Information
Molecular weight 2923.46274
Aliphatic index 104.4827586
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 987.2
Aromaticity 0.137931034
Average rotatable bonds 2.862068966
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 37
X logP energy -7.1484
Hydropathy 
Literature Information
Title Marked cell-type-specific differences in glycosylation of human interleukin-6.
DOI 10.1016/1043-4666(91)90018-9,
Publication Year 1991
PubMed ID 1883960,
Patent ID NA,
