SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02540

Signal sequence   MISPFLVLAIGTCLTNS

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P05186,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02540.cif

Structure  SPKB02540.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1780.17064

Aliphatic index  137.6470588

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  644.14

Aromaticity  0.058823529

Average rotatable bonds  3.235294118

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  25

X logP energy  -5.2537

Hydropathy 



Literature Information


Title  Chemical nature of intestinal-type alkaline phosphatase in human kidney.

DOI  NA,

Publication Year  1992

PubMed ID  1458595,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.