General Information
SPKB ID SPKB02539
Signal sequence MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEG
Length 48
Organism Homo sapiens (Human)
UniProt ID P05164,
Motif 1..48
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6BMT,
Predicted Structure ID SPKB02539.cif
Physicochemical Information
Molecular weight 4947.96334
Aliphatic index 113.9583333
Isoelectric point 4.426306407
Charge (pH=7) -1.122266748
Topological polar surface area 1755.71
Aromaticity 0.0625
Average rotatable bonds 3.25
Number of hydrogen bond donors 61
Number of hydrogen bond acceptors 65
X logP energy -12.13553
Hydropathy 
Literature Information
Title Glycosylation pattern of mature dimeric leukocyte and recombinant monomeric myeloperoxidase: glycosylation is required for optimal enzymatic activity.
Publication Year 2010
PubMed ID 20332087,
Patent ID NA,
