SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02538

Signal sequence   MRLKNLTFIIILIISGELYA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P05160,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8CMT,

Predicted Structure ID  SPKB02538.cif

Structure  SPKB02538.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2321.88994

Aliphatic index  180.5

Isoelectric point  9.297359792

Charge (pH=7)   0.998610663

Topological polar surface area  845.22

Aromaticity  0.1

Average rotatable bonds  3.95

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -1.87463

Hydropathy 



Literature Information


Title  Amino acid sequence of the b subunit of human factor XIII, a protein composed of ten repetitive segments.

DOI  10.1021/bi00364a027,

Publication Year  1986

PubMed ID  3021194,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.