SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02536

Signal sequence   MQLFLLLCLVLLSPQGASL

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P05154,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02536.cif

Structure  SPKB02536.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2059.59624

Aliphatic index  184.7368421

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  704.97

Aromaticity  0.052631579

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  -2.2518

Hydropathy 



Literature Information


Title  Protein C inhibitor from human plasma: characterization of native and cleaved inhibitor and demonstration of inhibitor complexes with plasma kallikrein.

DOI  NA,

Publication Year  1989

PubMed ID  2556811,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.