SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02534

Signal sequence   MRMLLHLSLLALGAAYVYA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P05113,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02534.cif

Structure  SPKB02534.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2106.61534

Aliphatic index  159.4736842

Isoelectric point  9.174205036

Charge (pH=7)   1.087189251

Topological polar surface area  738.39

Aromaticity  0.105263158

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -1.60753

Hydropathy 



Literature Information


Title  Structure of recombinant human interleukin 5 produced by Chinese hamster ovary cells.

DOI  10.1093/oxfordjournals.jbchem.a123041,

Publication Year  1990

PubMed ID  2361960,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.