SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02532

Signal sequence   MLPGLALLLLAAWTARA

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P05067,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02532.cif

Structure  SPKB02532.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1781.23264

Aliphatic index  167.0588235

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  618.05

Aromaticity  0.058823529

Average rotatable bonds  3.176470588

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  21

X logP energy  -1.21003

Hydropathy 



Literature Information


Title  Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

DOI  10.1038/nbt810,

Publication Year  2003

PubMed ID  12665801,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.