General Information
SPKB ID SPKB02530
Signal sequence MRSAAVLALLLCAGQVIA
Length 18
Organism Bos taurus (Bovine)
UniProt ID P05059,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02530.cif
Physicochemical Information
Molecular weight 1800.25114
Aliphatic index 168.3333333
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 683.24
Aromaticity 0
Average rotatable bonds 3.277777778
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 24
X logP energy -4.88273
Hydropathy
Literature Information
Title Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting chromogranin a into active catestatin secreted from neuroendocrine chromaffin cells.
DOI 10.1021/bi0300433,
Publication Year 2003
PubMed ID 12795588,
Patent ID NA,