SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02528

Signal sequence   MLRGPGPGRLLLLAVLCLGTSVRC

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P04937,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02528.cif

Structure  SPKB02528.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2496.13204

Aliphatic index  142.0833333

Isoelectric point  10.51794918

Charge (pH=7)   2.874024934

Topological polar surface area  941.2

Aromaticity  0

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  33

X logP energy  -7.48309

Hydropathy 



Literature Information


Title  Peptidomics for Studying Limited Proteolysis.

DOI  10.1021/acs.jproteome.5b00820,

Publication Year  2015

PubMed ID  26479776,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.