General Information
SPKB ID SPKB02527
Signal sequence MANLGYWLLALFVTMWTDVGLC
Length 22
Organism Mus musculus (Mouse)
UniProt ID P04925,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7TD6,
Predicted Structure ID SPKB02527.cif
Physicochemical Information
Molecular weight 2518.04444
Aliphatic index 124.0909091
Isoelectric point 3.749971056
Charge (pH=7) -1.064394347
Topological polar surface area 847.08
Aromaticity 0.181818182
Average rotatable bonds 3.454545455
Number of hydrogen bond donors 31
Number of hydrogen bond acceptors 31
X logP energy -1.3891
Hydropathy
Literature Information
Title Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie.
DOI 10.1111/j.1432-1033.1988.tb13883.x,
Publication Year 1988
PubMed ID 2894984,
Patent ID NA,